GOV.UK notes that RSV is a common respiratory virus that usually causes mild, cold-like symptoms (it is in the same family as the human parainfluenza viruses and mumps and measles viruses). While most RSV infections usually cause mild illness, infants aged less than 6 months may develop conditions such as bronchiolitis and pneumonia, resulting in hospital admissions. By age 2 years, most children have had at least one RSV infection as noted by the Lancet's website. Therefore, admissions for the 0 to 4-year-old age group were analysed between April 2020 and March 2025. Compared to the previous winter modelling report, narrower ICD-10 codes were used to deduce RSV admissions that are specific to the pathogen (J12.1, J20.5, J21.0 and B97.4 instead of J20-J22 that covers all cases of bronchitis and bronchiolitis).
Starting in August 2024 for Scotland and September 2024 for England and Wales and as noted by GOV.UK, the UK became the first country to introduce RSV vaccines for pregnant women and adults aged 75 to 79. The NHS adult vaccine campaign includes a routine program where older adults are offered the RSV vaccination within 12 weeks of their 75th birthday and a one-off catch-up campaign for those aged 75 to 79. The maternal vaccination is expected to protect both expectant mothers and their babies from serious illness. Data for winter of 2024 to 2025 is now available to assess the outcomes following the first year of the RSV vaccination programme’s implementation.
Figure 6: 7-day rolling average of daily paediatric RSV admissions (ages 0 to 4), between April 2020 and March 2025 [note 1].
Description of figure 6: a line chart showing recorded daily Respiratory Syncytial Virus (RSV) admissions among children aged 0 to 4 in Wales.
Source: Digital Health and Care Wales (DHCW).
[Note 1]: Data includes diagnosis codes J12.1, J20.5, J21.0 and B97.4 from ICD-10.
During the 2024 to 2025 winter season, there were a total of 1,020 RSV paediatric (aged 0 to 4 years) admissions. This was a 26% decrease compared to the previous season and 23% decrease compared to the 3-year average. Age groups 1 to 6 months, 7 to 12 months and 1 to 4 years showed a decrease of 33%, 26% and 14% respectively compared to the 2023 to 2024 season. The greater reductions among the youngest age groups may reflect the temporary protection effects of the maternal vaccination which is likely to last ~ 6 months after birth. The admissions showed a peak of 19 daily admissions on 17 to 18 November 2024, a week later than the previous season. Over the last three winters, the RSV admissions peaked between 11 November and 8 December.
UKHSA (United Kingdom Health Security Agency) collates data on test-confirmed hospitalised RSV cases in England through the Severe Acute Respiratory Infection (SARI) Watch surveillance system which is a sentinel system that collects data from small network of acute NHS trusts reporting voluntarily. SARI data on GOV.UK suggests that hospital admission rate (excluding Intensive Care Unit (ICU) or High Dependency Unit (HDU)) among those aged under 5 years, peaked at 46.17 per 100,000 in week 48 2024. This is similar to the peak observed in 2023 to 2024 winter (including ICU or HDU) noted on GOV.UK where the hospitalisation rate peaked at 44.83 per 100,000 in week 48 2023, with the data noted on GOV.UK. Cumulative rates for both seasons are similar as well, although 2023 to 2024 is slightly lower than 2024 to 2025. This indicates that there are no significant reductions in winter 2024 to 2025 compared to the previous season among children under 5 years in England. Nevertheless, it remains possible that younger cohorts (1 to 6 months that derive benefits from maternal vaccination) could experience decreases. However, we do not have access to the granular data for these age groups for England to investigate further.
To generate admissions and occupancy scenarios, a modified version of Susceptible, Exposed, Infectious, Recovered, and Susceptible (SEIRS) compartment transmission model (SE2I2RS), incorporating two compartments for the pre-infectious and infectious states was created. (For more details, please refer to the ‘Effect of respiratory syncytial virus (RSV) vaccines on hospital admissions in Wales’ paper). The model was calibrated using admission data from the winters of 2022 to 2023 and 2023 to 2424. With these two winters serving as reference points, vaccine uptake rates among target groups—specifically pregnant women and adults aged 75 to 79 - were varied between 0% and 90% and a range of scenarios were created. For this winter modelling report, the modelling scenarios with Vaccine Uptake (VU) values of 30% and 60% were chosen and are presented below.
Table 2: Names of RSV admission and occupancy scenarios, including details of the SEIR model assumptions (vaccine uptake and reference winter). [Note 1].
| Scenario name | Reference Season | Vaccine uptake |
|---|
| High season, VU= 30% | 2022 to 2023 winter | 30% |
| High season, VU= 60% | 2022 to 2023 winter | 60% |
| Low season, VU= 30% | 2023 to 2024 winter | 30% |
| Low season, VU= 60% | 2023 to 2024 winter | 60% |
[Note 1]: VU refers to vaccine uptake (%)
Figure 7: daily RSV paediatric admissions (ages 0 to 4 years) scenarios – winter 2025 to 2026.
Description of figure 7: A line chart representing projected scenarios for RSV admissions among children aged 0 to 4 years in Wales, factoring in vaccination uptake rates of 30% and 60% for a high season and a low season.
Source: SRE calculations.
High season scenarios with VU= 30% and VU= 60% indicate a projected peak of 18 admissions between 8 and 11 December 2025, while low season scenarios with VU= 30% and VU= 60% forecast a peak of 16 to 17 admissions between 18 and 19 November. Please note that the effect of the vaccination is more apparent in younger age groups <1 years old where the model estimates reductions 9 to 31% in infants aged 1 to 6 months, and 3 to 12% reduction in 7 to 12 months with a vaccine uptake range between 0 to 90% (See the ‘Effect of respiratory syncytial virus (RSV) vaccines on hospital admissions in Wales’ paper). The model suggests that improving the vaccine uptake rate from 30% to 60% could reduce RSV admissions (in 0 to 4 year olds) over the 2025 to 2026 winter season from 1,345 to 1,252 admissions for the high scenario and from 1,299 to 1,222 admissions for the low scenario.
Figure 8: 7-day rolling average of daily paediatric RSV occupancy (ages 0 to 4), between April 2020 and March 2025 [note 1].
Description of Figure 8: a line chart of RSV-related bed occupancy among children aged 0 to 4 years in Wales, broken down.
Source: Digital Health and Care Wales (DHCW).
[Note 1]: Data includes diagnosis codes J12.1, J20.5, J21.0 and B97.4 from ICD-10
Bed occupancy due to RSV in children aged 0 to 4 years peaked at 29 beds per day on November 30, 2024, lower than the previous year’s peak of 33 beds per day on 6 November 2023.
Length of stay for younger age groups remained unchanged in winter 2024 to 2025 compared to previous winters. Children aged 1 to 4 years with RSV stayed an average of 1.85 days during the 2024 to 2025 season, similar to the data from the past three years. Similarly, the length of stay among infants aged 1 to 6 months and 7 to 12 months was comparable to previous years.
Figure 9: Daily RSV paediatric (ages 0 to 4) occupancy scenarios – winter 2025 to 2026
Description of figure 9: A line chart representing projected scenarios for RSV bed occupancy among children aged 0 to 4 years in Wales, factoring in vaccination uptake rates of 30% and 60% for a high season and a low season.
Source: SRE calculations.
Using the length of stay data from the 2022 to 2023 and 2023 to 2024 winters, RSV occupancy scenarios were generated from the output of the SE2I2R model. In high season occupancy scenarios with vaccine uptake (VU) levels at 30% and 60%, projections indicate a peak demand of 43 to 45 beds between 8 and 12 December 2025. In low season occupancy scenarios with VU at 30% and 60%, the estimated peak in beds ranges from 39 to 42 beds during 19 to 20 November 2025.